Col25a1^tm2.1Tiwa
Targeted Allele Detail

Summary

• Symbol: Col25a1^tm2.1Tiwa
• Name: collagen, type XXV, alpha 1; targeted mutation 2.1, Takeshi Iwatsubo
• MGI ID: MGI:7855952
• Synonyms: Col25a1^flox
• Gene: Col25a1 Location: Chr3:129973992-130393533 bp, + strand Genetic Position: Chr3, 59.99 cM, cytoband H1
• Alliance: Col25a1^tm2.1Tiwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296800
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked beta-geo selection cassette were inserted to surround exon 2. The selection cassette was removed via FLP-mediated recombination in the germline. (J:296800)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col25a1 Mutation: 46 strains or lines available

References

• Original: J:296800 Munezane H, et al., Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder. Cell Rep. 2019 Dec 24;29(13):4362-4376.e6
• All: 1 reference(s)