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Tg(Rr594-EGFP)#Mrub
Transgene Detail
Summary
Symbol: Tg(Rr594-EGFP)#Mrub
Name: transgene insertion, Marcelo Rubinstein
MGI ID: MGI:7852716
Synonyms: -18kbPomc-EGFP
Transgene: Tg(Rr594-EGFP)#Mrub  Location: unknown  
Alliance: Tg(Rr594-EGFP)#Mrub page
Mutation
origin
Strain of Origin:  FVB/NJ
Mutation
description
Allele Type:    Endonuclease-mediated (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene insert consists of hypothalamic neuron-specific Pomc enhancer nPE3, the Fos gene minimal promoter and an EGFP reporter gene cassette. Three mouse lines were created. (J:357475)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:357475 Rojo D, et al., A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2322692121
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory