Tox2^em1Abh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tox2^em1Abh
• Name: TOX high mobility group box family member 2; endonuclease-mediated mutation 1, Avinash Bhandoola
• MGI ID: MGI:7834410
• Synonyms: Tox2 flox
• Gene: Tox2 Location: Chr2:163045047-163166092 bp, + strand Genetic Position: Chr2, 84.14 cM
• Alliance: Tox2^em1Abh page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to insert loxP sites flanking exon 5. (J:360412)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tox2 Mutation: 31 strains or lines available

References

• Original: J:360412 Das A, et al., Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut. Immunity. 2024 May 14;57(5):1019-1036.e9
• All: 1 reference(s)