Abca4^{tm1(ABCA4)Cya}
Targeted Allele Detail

Summary

• Symbol: Abca4^{tm1(ABCA4)Cya}
• Name: ATP-binding cassette, sub-family A member 4; targeted mutation 1, Cyagten Biosciences
• MGI ID: MGI:7797879
• Gene: Abca4 Location: Chr3:121838092-121973772 bp, + strand Genetic Position: Chr3, 52.94 cM
• Alliance: Abca4^{tm1(ABCA4)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Abca4^{tm1(ABCA4)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ABCA4 (24)

  Abca4

  (MGI:109424)

• Mutation details: The sequences from the ATG start codon to the TGA stop codon of the mouse Abca4 gene were replaced with the sequences from the ATG start codon to the TGA stop codon of the human ABCA4 gene. (J:326541)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abca4 Mutation: 109 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)