Cygb^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Cygb^tm1.1Geno
• Name: cytoglobin; targeted mutation 1.1, Genoway
• MGI ID: MGI:7797306
• Gene: Cygb Location: Chr11:116536421-116544887 bp, - strand Genetic Position: Chr11, 81.45 cM, cytoband E2
• Alliance: Cygb^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:277923
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP511 site and FRT flanked neo cassette were inserted upstream of exon 2 and a loxP511 site was inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination deleted the neo cassette and exon 2. (J:277923)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cygb Mutation: 18 strains or lines available

References

• Original: J:277923 Yassin M, et al., Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice. Sci Rep. 2018 May 2;8(1):6905
• All: 2 reference(s)