Slc30a10^tm1.1Cmsu
Targeted Allele Detail

Summary

• Symbol: Slc30a10^tm1.1Cmsu
• Name: solute carrier family 30, member 10; targeted mutation 1.1, Cam-Su Genomic Resource Center
• MGI ID: MGI:7790684
• Synonyms: Slc30a10^flox
• Gene: Slc30a10 Location: Chr1:185187045-185200959 bp, + strand Genetic Position: Chr1, 89.53 cM
• Alliance: Slc30a10^tm1.1Cmsu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:359677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT site, lacZ, loxP site, neomycin resistance gene, FRT site, and loxP site were inserted upstream of exon 3 and a third loxP site was inserted downstream of exon 4. The lacZ-neo cassette was removed via flp-mediated recombination. (J:359677)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc30a10 Mutation: 21 strains or lines available

References

• Original: J:359677 Shi JH, et al., Fructose overconsumption impairs hepatic manganese homeostasis and ammonia disposal. Nat Commun. 2023 Dec 1;14(1):7934
• All: 1 reference(s)