Fbp1^tm1.1Cmsu
Targeted Allele Detail

Summary

• Symbol: Fbp1^tm1.1Cmsu
• Name: fructose bisphosphatase 1; targeted mutation 1.1, Cam-Su Genomic Resource Center
• MGI ID: MGI:7790676
• Synonyms: Fbp1^flox
• Gene: Fbp1 Location: Chr13:63012567-63036096 bp, - strand Genetic Position: Chr13, 32.74 cM, cytoband B3-C1
• Alliance: Fbp1^tm1.1Cmsu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:359678
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT site, lacZ, loxP site, neomycin resistance gene, FRT site, and loxP site were inserted upstream of exon 2 and a third loxP site was inserted downstream of exon 2. The lacZ and neomycin resistance were removed via flp-mediated recombination. (J:359678)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbp1 Mutation: 25 strains or lines available

References

• Original: J:359678 Bai Q, et al., Hepatic but not Intestinal FBP1 Is Required for Fructose Metabolism and Tolerance. Endocrinology. 2023 Apr 17;164(6)
• All: 1 reference(s)