Plgrkt^tm3.1Lmls
Targeted Allele Detail

Summary

• Symbol: Plgrkt^tm3.1Lmls
• Name: plasminogen receptor, C-terminal lysine transmembrane protein; targeted mutation 3.1, Lindsey Miles
• MGI ID: MGI:7786679
• Synonyms: Plg-RKT^K147A
• Gene: Plgrkt Location: Chr19:29326004-29339340 bp, - strand Genetic Position: Chr19, 23.85 cM
• Alliance: Plgrkt^tm3.1Lmls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: iTL BF1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: The targeting vector was designed to introduce K147A point mutation (c.439_440delinsGC,p.Lys147Ala, AAA to GCA) into exon 6 of the mouse Plgrkt gene. The vector also contained FRT flanked Neo selection cassette positioned downstream of exon 6, which Flp recombinase removed during ES clone expansion. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plgrkt Mutation: 8 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)