Bmal1^em1Mngq
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bmal1^em1Mngq
• Name: basic helix-loop-helix ARNT like 1; endonuclease-mediated mutation 1, Qing-Jun Meng
• MGI ID: MGI:7786664
• Synonyms: Bmal1^Venus, Venus::BMAL1
• Gene: Bmal1 Location: Chr7:112806672-112913333 bp, + strand Genetic Position: Chr7, 59.17 cM, cytoband F2-F3
• Alliance: Bmal1^em1Mngq page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• CRISPR-targeting inserted a Venus reporter gene at the translation initiation site. (J:288347)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmal1 Mutation: 137 strains or lines available

References

• Original: J:288347 Yang N, et al., Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator. PLoS Genet. 2020 Apr;16(4):e1008729
• All: 3 reference(s)