Adam39^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adam39^em1(IMPC)J
• Name: a disintegrin and metallopeptidase domain 39; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7785574
• Gene: Adam39 Location: Chr8:41276046-41279898 bp, + strand Genetic Position: Chr8, 23.89 cM
• Alliance: Adam39^em1(IMPC)J page
• IMPC: Adam39 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences: TATTCAATATCTCTAGCCAG and ATTCAATGACACAAAGTCCT. This resulted in a 2,290 bp deletion of Chr8:40,824,670-40,826,959 (GRCm38/mm10) that removes exon ENSMUSE00000466894. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Adam39 Mutation: 40 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)