Nrxn3^tm1.1Schei
Targeted Allele Detail

Summary

• Symbol: Nrxn3^tm1.1Schei
• Name: neurexin III; targeted mutation 1.1, Peter Scheiffele
• MGI ID: MGI:7785236
• Synonyms: Nrxn3^ex21flox
• Gene: Nrxn3 Location: Chr12:88689646-90301709 bp, + strand Genetic Position: Chr12, 42.94 cM
• Alliance: Nrxn3^tm1.1Schei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239448
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129/Sv x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was placed 718 bp upstream of exon 2 and a loxP-Frt-PGKneo-Frt cassette was inserted 840 bp downstream of the same exon. The selection cassette was removed via FLP-mediated recombination in the germline. (J:239448)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrxn3 Mutation: 81 strains or lines available

References

• Original: J:239448 Nguyen TM, et al., An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus. Elife. 2016 Dec 13;5:e22757
• All: 1 reference(s)