Col19a1^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Col19a1^tm1.1Itl
• Name: collagen, type XIX, alpha 1; targeted mutation 1.1, Ingenious Targeting Laboratory
• MGI ID: MGI:7783617
• Synonyms: Col19a1^fl
• Gene: Col19a1 Location: Chr1:24300971-24626553 bp, - strand Genetic Position: Chr1, 9.99 cM, cytoband A3
• Alliance: Col19a1^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296215
• Parent Cell Line: iTL HF4 (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were cloned into intron 3, and a Frt-LoxP-Neo-Frt-LoxP cassette was cloned into intron 4. The neo cassette was removed via FLP-mediated recombination in the germline, leaving loxP sites flanking exon 3. (J:296215)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col19a1 Mutation: 79 strains or lines available

References

• Original: J:296215 Su J, et al., Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses. J Neurosci. 2020 Sep 23;40(39):7421-7435
• All: 2 reference(s)