C3ar1^tm1.1Kohl
Targeted Allele Detail

Summary

• Symbol: C3ar1^tm1.1Kohl
• Name: complement component 3a receptor 1; targeted mutation 1.1, Jorg Kohl
• MGI ID: MGI:7782580
• Synonyms: C3ar1-TDTomato
• Gene: C3ar1 Location: Chr6:122824099-122833116 bp, - strand Genetic Position: Chr6, 57.93 cM, cytoband F1
• Alliance: C3ar1^tm1.1Kohl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A tdTomato gene was inserted in-frame with the coding sequence of C3ar1 after the ATG initiation codon. LoxP sites were also inserted to flank the entire coding region of the mutated gene. An adjacent frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:251199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C3ar1 Mutation: 34 strains or lines available

References

• Original: J:251199 Quell KM, et al., Monitoring C3aR Expression Using a Floxed tdTomato-C3aR Reporter Knock-in Mouse. J Immunol. 2017 Jul 15;199(2):688-706
• All: 4 reference(s)