Tg(CD2-Tcr*)V316Ybe
Transgene Detail

Summary

• Symbol: Tg(CD2-Tcr*)V316Ybe
• Name: transgene insertion V316, Yasmine Belkaid
• MGI ID: MGI:7782512
• Synonyms: SA2-Tg
• Transgene: Tg(CD2-Tcr*)V316Ybe Location: unknown
• Alliance: Tg(CD2-Tcr*)V316Ybe page

Transgene origin

• Strain of Origin: C57BL/6NCr

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Clonal TCR pairs were identified and used in a hybridoma reconstitution screening assay to identify S. aureus-reactive TCR heterodimers from mice infected with S. aureus (42F02) by an intradermal injection in the ear. A single S. aureus-specific TCR pair was cloned into a human CD2-expression vector. Founder line V316 was established. (J:101977, J:336531)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:336531 Enamorado M, et al., Immunity to the microbiota promotes sensory neuron regeneration. Cell. 2023 Feb 2;186(3):607-620.e17
• All: 2 reference(s)