Tg(Fabp4-Cisd1)1Pesch
Transgene Detail

Summary

• Symbol: Tg(Fabp4-Cisd1)1Pesch
• Name: transgene insertion 1, Philipp E Scherer
• MGI ID: MGI:7781890
• Synonyms: mitoNEET TG, MitoN-Tg
• Transgene: Tg(Fabp4-Cisd1)1Pesch Location: unknown
• Alliance: Tg(Fabp4-Cisd1)1Pesch page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-Cisd1)1Pesch expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cisd1 (MGI:1261855)

• Tg(Fabp4-Cisd1)1Pesch expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fabp4 (MGI:88038)

• Mutation details: The mouse 5.4-kb Fabp4 (aP2) promoter was used to drive overexpression of Cisd1. Expression of the transgene is limited to adipocytes. (J:193426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:193426 Kusminski CM, et al., MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nat Med. 2012 Oct;18(10):1539-49
• All: 4 reference(s)