Gt(ROSA)26Sor^tm1(Rere)Olp
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(Rere)Olp
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Olivier Pourquie
• MGI ID: MGI:7781548
• Synonyms: Rosa26^Rere-HA, RS-Rere-HA
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(Rere)Olp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252998
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^tm1(Rere)Olp expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rere (MGI:2683486)	with C-terminal HA tags; conditionally expressed

• Mutation details: The following elements were inserted into an intron: a loxP site flanked STOP cassette and a mouse Rere cDNA with 2x sequence for an HA tag inserted in-frame before the stop codon. This allele will only express the inserted gene after Cre-mediated removal of the STOP cassette. (J:252998)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1061 strains or lines available

References

• Original: J:252998 Vilhais-Neto GC, et al., The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry. Nat Commun. 2017 Sep 28;8(1):728
• All: 1 reference(s)