Rr432^tm1.1Ploen
Targeted Allele Detail

Summary

• Symbol: Rr432^tm1.1Ploen
• Name: regulatory region 432; targeted mutation 1.1, Diethard Tautz
• MGI ID: MGI:7779642
• Gene: Rr432 Location: unknown Genetic Position: Chr8, Syntenic
• Alliance: Rr432^tm1.1Ploen page

Mutation origin

• Mouse Generated: Earliest citation of chimera generation: J:338778
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The alternative spermatid-specific-isoform-alpha1-(isoform 6)-associated Map2k7 promoter, located in intron 1 (GRCm39:chr8:4289574-4290166), was replaced with an FRT site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent Flp-mediated recombination. (J:338778)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr432 Mutation: 0 strains or lines available

References

• Original: J:338778 Heinen T, et al., Evolution of a New Testis-Specific Functional Promoter Within the Highly Conserved Map2k7 Gene of the Mouse. Front Genet. 2021;12:812139
• All: 1 reference(s)