Del(13Rr406303-Rr406540)1Ezk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(13Rr406303-Rr406540)1Ezk
• Name: deletion, Chr 3, Evgeny Z Kvon 1
• MGI ID: MGI:7764498
• Synonyms: deltahs267-853
• Gene: Del(13Rr406303-Rr406540)1Ezk Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Strain of Origin: FVB

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Mutation details: Mir9-2 forebrain enhancers Rr406303 (hs267), Rr406302 (hs266) and Rr406540 (hs853) were targeted using sgRNAs with CRISPR/Cas9 technology, resulting in their deletion (GRCm39:chr13:84713171-84903078). (J:347410)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(13Rr406303-Rr406540)1Ezk Mutation: 0 strains or lines available

References

• Original: J:347410 Chen Z, et al., Increased enhancer-promoter interactions during developmental enhancer activation in mammals. Nat Genet. 2024 Apr;56(4):675-685
• All: 1 reference(s)