Mirc20^em1Sjli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mirc20^em1Sjli
• Name: microRNA cluster 20, including Mir302b through Mir367; endonuclease-mediated mutation 1, Si-jia Liang
• MGI ID: MGI:7748723
• Synonyms: miR-302^flox
• Gene: Mirc20 Location: Chr3:127338877-127339456 bp Genetic Position: Chr3, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mirc20^em1Sjli involves 5 genes/genome features (Mir302b, Mir302c, Mir302a ...) View all
• Mutation details: The five miRNAs in the Mirc20 (miR-302) cluster (Mir302a, Mir302b, Mir302c, Mir302d, and Mir367) were flanked by loxP sites via CRISPR/Cas9 technology. (J:325576)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc20 Mutation: 1 strain or line available

References

• Original: J:325576 Liu YY, et al., MicroRNA-302a promotes neointimal formation following carotid artery injury in mice by targeting PHLPP2 thus increasing Akt signaling. Acta Pharmacol Sin. 2021 Apr;42(4):550-559
• All: 1 reference(s)