Tox4^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tox4^em3Smoc
• Name: TOX high mobility group box family member 4; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7748719
• Synonyms: Tox4^{em1(flox)Smoc}
• Gene: Tox4 Location: Chr14:52516603-52532966 bp, + strand Genetic Position: Chr14, 26.88 cM
• Alliance: Tox4^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing technology was used to mediate a knock-in of loxP sites flanking exons 46. (J:336398)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tox4 Mutation: 33 strains or lines available

References

• Original: J:336398 Wang T, et al., Tox4 regulates transcriptional elongation and reinitiation during murine T cell development. Commun Biol. 2023 Jun 7;6(1):613
• All: 1 reference(s)