Taok1^em1Lmjn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Taok1^em1Lmjn
• Name: TAO kinase 1; endonuclease-mediated mutation 1, Lauryl Nutter
• MGI ID: MGI:7735174
• Gene: Taok1 Location: Chr11:77419988-77498641 bp, - strand Genetic Position: Chr11, 46.64 cM, cytoband B5
• Alliance: Taok1^em1Lmjn page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Bxb1 integrase mRNA and a DNA minicircle containing a single Bxb1 attB-GT site and loxP-flanked genomic DNA (Chr11:77465754 to 77467045 GRCm39) including exon ENSMUSE00000520605 were microinjected into C57BL/6NCrl-derived embryos with the Taok1 (MGI:7293333) allele that contains a single Bxb1 attB-GT site at the deletion junction. This insertion is predicted to restore wild-type gene function and create a conditional allele. Cre-mediated deletion of the loxP-flanked region is predicted to generate a null allele equivalent to Taok1^em1(IMPC)Tcp. (J:345353)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taok1 Mutation: 46 strains or lines available

References

• Original: J:345353 Nutter L, Direct Data Submissions for Lauryl Nutter. 2024
• All: 1 reference(s)