Rr558^em1Yzhou
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr558^em1Yzhou
• Name: regulatory region 558; endonuclease-mediated mutation 1, Yan Zhou
• MGI ID: MGI:7734741
• Synonyms: neCtnnb1^KO
• Gene: Rr558 Location: Chr9:120698128-120700407 bp Genetic Position: Chr9, Syntenic
• Alliance: Rr558^em1Yzhou page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutations: Intergenic deletion, Intragenic deletion
• Mutation details: The Ctnnb1 enhancer was targeted using sgRNAs with CRISPR/Cas9 technology, resulting in its deletion. (J:339243)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr558 Mutation: 0 strains or lines available

References

• Original: J:339243 Wang J, et al., A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022 Aug 2;8(1):74
• All: 1 reference(s)