Nr1h3^tm1.1Gust
Targeted Allele Detail

Summary

• Symbol: Nr1h3^tm1.1Gust
• Name: nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, Jan-Ake Gustafsson
• MGI ID: MGI:7720839
• Gene: Nr1h3 Location: Chr2:91014406-91033179 bp, - strand Genetic Position: Chr2, 50.52 cM
• Alliance: Nr1h3^tm1.1Gust page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site in intron 3, frt and loxP sites in intron 4, and a third loxP site in intron 6 were inserted into the Nr1h3 gene. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nr1h3 Mutation: 32 strains or lines available

References

• Original: J:298710 Chan CT, et al., Liver X receptors are required for thymic resilience and T cell output. J Exp Med. 2020 Oct 5;217(10)
• All: 4 reference(s)