Rr150^tm2.1Erpi
Targeted Allele Detail

Summary

• Symbol: Rr150^tm2.1Erpi
• Name: regulatory region 150; targeted mutation 2.1, Eric Pinaud
• MGI ID: MGI:7720005
• Synonyms: MARsEmu^delta
• Gene: Rr150 Location: Chr12:113390871-113391349 bp Genetic Position: Chr12, Syntenic
• Alliance: Rr150^tm2.1Erpi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342746
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details : The sequence containing the Igh enhancer cEmu ( Rr554 and Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
  • Carrying any Rr150 Mutation: 0 strains or lines available
• References:
  • Original: J:342746 Martin OA, et al., The IgH Emicro-MAR regions promote UNG-dependent error-prone repair to optimize somatic hypermutation. Front Immunol. 2023;14:1030813
  • All: 1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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