Senp2^tm3.2Whsu
Targeted Allele Detail

Summary

• Symbol: Senp2^tm3.2Whsu
• Name: SUMO/sentrin specific peptidase 2; targeted mutation 3.2, Wei Hsu
• MGI ID: MGI:7718781
• Gene: Senp2 Location: Chr16:21828234-21868019 bp, + strand Genetic Position: Chr16, 12.98 cM, cytoband B1
• Alliance: Senp2^tm3.2Whsu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250113
• Parent Cell Line: CSL3 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 3 and a floxed pgk-neo cassette was inserted in intron 4 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 4. (J:250113)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Senp2 Mutation: 54 strains or lines available

References

• Original: J:250113 Maruyama EO, et al., Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development. Sci Rep. 2016 Feb 17;6:20999
• All: 1 reference(s)