Rr67142^em1Pero
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr67142^em1Pero
• Name: regulatory region 67142; endonuclease-mediated mutation 1, Pedro P Rocha
• MGI ID: MGI:7718618
• Synonyms: CTCFdelta(C5)
• Gene: Rr67142 Location: Chr3:34814001-34814400 bp Genetic Position: Chr3, Syntenic
• Alliance: Rr67142^em1Pero page

Mutation origin

• Strain of Origin: C57BL/6NCr

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutations: Insertion, Intergenic deletion
• Mutation details : CTCF-binding site C5, part of Sox2 distal super-enhancer SCR ( Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
  • Carrying any Rr67142 Mutation: 0 strains or lines available
• References:
  • Original: J:342647 Chakraborty S, et al., Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nat Genet. 2023 Feb;55(2):280-290
  • All: 1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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