Rr544em1Tboz
Endonuclease-mediated Allele Detail
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Symbol: |
Rr544em1Tboz |
Name: |
regulatory region 544; endonuclease-mediated mutation 1, Thomas Bozza |
MGI ID: |
MGI:7714929 |
Synonyms: |
deltaTE1 |
Gene: |
Rr544 Location: Chr10:23806280-23806978 bp Genetic Position: Chr10, Syntenic
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Alliance: |
Rr544em1Tboz page
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Allele Type: |
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Endonuclease-mediated (Modified regulatory region) |
Mutation: |
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Intergenic deletion
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Mutation details: The Taar cluster enhancer, located between Taar1 and Taar2, was targeted using sgRNAs with CRISPR/Cas9 technology, resulting in a 993 bp deletion (GRCm39:chr10:23,806,234-23,807,226). The allele was created in zygotes heterozygous for the Taar1tm1Tboz and Taar4tm1.1Tboz alleles and Taar1tm1Tboz Rr544em1Tboz mice were selected for experiments.
(J:343906)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr544 Mutation: |
0 strains or lines available
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Original: |
J:343906 Shah A, et al., Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers. Nat Commun. 2021 Jun 18;12(1):3797 |
All: |
1 reference(s) |
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