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Rr544em1Tboz
Endonuclease-mediated Allele Detail
Summary
Symbol: Rr544em1Tboz
Name: regulatory region 544; endonuclease-mediated mutation 1, Thomas Bozza
MGI ID: MGI:7714929
Synonyms: deltaTE1
Gene: Rr544  Location: Chr10:23806280-23806978 bp  Genetic Position: Chr10, Syntenic
Alliance: Rr544em1Tboz page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Modified regulatory region)
Mutation:    Intergenic deletion
 
Mutation detailsThe Taar cluster enhancer, located between Taar1 and Taar2, was targeted using sgRNAs with CRISPR/Cas9 technology, resulting in a 993 bp deletion (GRCm39:chr10:23,806,234-23,807,226). The allele was created in zygotes heterozygous for the Taar1tm1Tboz and Taar4tm1.1Tboz alleles and Taar1tm1Tboz Rr544em1Tboz mice were selected for experiments. (J:343906)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr544 Mutation:  0 strains or lines available
References
Original:  J:343906 Shah A, et al., Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers. Nat Commun. 2021 Jun 18;12(1):3797
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory