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Tg(tetO-LIPA)548Cyan
Transgene Detail
Summary
Symbol: Tg(tetO-LIPA)548Cyan
Name: transgene insertion 548, Cong Yan
MGI ID: MGI:7714581
Transgene: Tg(tetO-LIPA)548Cyan  Location: unknown  
Alliance: Tg(tetO-LIPA)548Cyan page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene consists of the CMV minimal promoter linked to seven Tet-responsive elements (7-TRE) , human LIPA cDNA, and the beta-globin polyadenylation signaling sequence. Six positive funders were identified and a founder line 548 was established. (J:101977, J:112356)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112356 Yan C, et al., Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice. Am J Pathol. 2006 Sep;169(3):916-26
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory