Glis3^tm4Amj
Targeted Allele Detail

Summary

• Symbol: Glis3^tm4Amj
• Name: GLIS family zinc finger 3; targeted mutation 4, Anton M Jetten
• MGI ID: MGI:7709765
• Synonyms: Glis3^fl
• Gene: Glis3 Location: Chr19:28236251-28657477 bp, - strand Genetic Position: Chr19, 22.88 cM
• Alliance: Glis3^tm4Amj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:353168
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 5 was flanked by loxP sites. A neomycin resistance gene and third loxP site were inserted downstream of the floxed exon 5. (J:353168)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glis3 Mutation: 40 strains or lines available

Notes

This allele was created in ES cells containing Glis3^tm2Amj.

References

• Original: J:353168 Scoville D, et al., GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors. J Endocrinol. 2019 Jul 1
• All: 3 reference(s)