Cct5^em1Guob
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cct5^em1Guob
• Name: chaperonin containing TCP1 subunit 5; endonuclease-mediated mutation 1, Bin Guo
• MGI ID: MGI:7709322
• Synonyms: Cct5^f
• Gene: Cct5 Location: Chr15:31590946-31601950 bp, - strand Genetic Position: Chr15, 13.02 cM, cytoband B3.2

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:350813
• Parent Cell Line: A3-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination inserted loxP sites around exon 4. (J:350813)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cct5 Mutation: 23 strains or lines available

References

• Original: J:350813 Li L, et al., The Chaperone Protein Cct5 is Essential for Hematopoietic Stem Cell Maintenance. Stem Cell Rev Rep. 2024 Apr;20(3):769-778
• All: 1 reference(s)