Gt(ROSA)26Sor^{tm2(CAG-MYC/Pisd)Funai}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-MYC/Pisd)Funai}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Katsuhiko Funai
• MGI ID: MGI:7707987
• Synonyms: PSD-MKI
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-MYC/Pisd)Funai} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288084
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(CAG-MYC/Pisd)Funai} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pisd (MGI:2445114)

• Mutation details: A construct containing a CAG promoter followed by a floxed stop-neo cassette and a myc-tagged mouse Pisd cDNA was inserted in intron 1 via homologous recombination. (J:288084)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1061 strains or lines available

References

• Original: J:288084 Heden TD, et al., Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv. 2019 Sep;5(9):eaax8352
• All: 2 reference(s)