Mirc22^tm1.1Akit
Targeted Allele Detail

Summary

• Symbol: Mirc22^tm1.1Akit
• Name: microRNA cluster 22, including Mir23b through Mir24-1; targeted mutation 1.1, Takayuki Akimoto
• MGI ID: MGI:7705324
• Gene: Mirc22 Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:267179
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted around Mir23b, Mir27b and Mir24-1 and an FRT flanked neo cassette and third loxP site were also inserted. Flp mediated recombination removed the neo cassette. (J:267179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc22 Mutation: 3 strains or lines available

References

• Original: J:267179 Oikawa S, et al., Role of endothelial microRNA-23 clusters in angiogenesis in vivo. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H838-H846
• All: 3 reference(s)