Pacc1^em2Bosm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pacc1^em2Bosm
• Name: proton activated chloride channel 1; endonuclease-mediated mutation 2, Markus Bosmann
• MGI ID: MGI:7703115
• Synonyms: PACC1-floxed
• Gene: Pacc1 Location: Chr1:191058109-191083111 bp, + strand Genetic Position: Chr1, 96.28 cM
• Alliance: Pacc1^em2Bosm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The allele was generated using CRISPR/cas9 endonuclease-mediated homology-directed repair (HDR) genome editing. Guide RNAs (5'-TCCTTGCTAAGCACCCGACTTGG-3' and 5'-GGACCCTTATACACTGTGCACGG-3') were used to target the introns flanking exons 3-4 of the proton activated chloride channel 1 (Pacc1) gene. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pacc1 Mutation: 24 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)