Arf1^tm2.1Towa
Targeted Allele Detail

Summary

• Symbol: Arf1^tm2.1Towa
• Name: ARF GTPase 1; targeted mutation 2.1, Toshio Watanabe
• MGI ID: MGI:7666679
• Gene: Arf1 Location: Chr11:59102237-59119042 bp, - strand Genetic Position: Chr11, 37.05 cM, cytoband B2
• Alliance: Arf1^tm2.1Towa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303911
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP site and FRT-flanked neo cassette were inserted downstream of exon 3 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:303911)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arf1 Mutation: 16 strains or lines available

References

• Original: J:303911 Sumiyoshi M, et al., Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation. J Immunol. 2021 Jan 15;206(2):366-375
• All: 2 reference(s)