Rr484em1Mam
Endonuclease-mediated Allele Detail
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Symbol: |
Rr484em1Mam |
Name: |
regulatory region 484; endonuclease-mediated mutation 1, Lothar Hennighausen |
MGI ID: |
MGI:7664593 |
Synonyms: |
Csn3-deltaE2-S |
Gene: |
Rr484 Location: Chr5:88072048-88073118 bp Genetic Position: Chr5, Syntenic
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Alliance: |
Rr484em1Mam page
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Allele Type: |
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Endonuclease-mediated (Modified regulatory region) |
Mutation: |
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Intergenic deletion
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Mutation details: The proximal Csn3 enhancer was deleted using sgRNAs (equivalent to CAGGTCATCCTATTGCCTCAAGG and GTGTAATGGTTCCCAGAAACAGG) with CRISPR/Cas9 technology, resulting in a 194 bp deletion. The deletion includes the GAS and GR motifs but not the NFIB motifs.
(J:341588)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr484 Mutation: |
0 strains or lines available
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Original: |
J:341588 Lee HK, et al., Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands. Nat Commun. 2023 Aug 17;14(1):4992 |
All: |
1 reference(s) |
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