Scn2a^{tm2(SCN2A)Cya}
Targeted Allele Detail

Summary

• Symbol: Scn2a^{tm2(SCN2A)Cya}
• Name: sodium channel, voltage-gated, type II, alpha; targeted mutation 2, Cyagen Biosciences
• MGI ID: MGI:7657322
• Synonyms: S100a4^{em1(P2A-CreERT2)}
• Gene: Scn2a Location: Chr2:65451115-65597791 bp, + strand Genetic Position: Chr2, 38.61 cM
• Alliance: Scn2a^{tm2(SCN2A)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Scn2a^{tm2(SCN2A)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SCN2A (6326)

  Scn2a

  (MGI:98248)

• Mutation details: The sequence from the ATG start codon to the TAA stop codon of mouse Scn2a was replaced with the sequence from the ATG start codon to the TAA stop codon of human SCN2A. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scn2a Mutation: 94 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)