Mecp2^{tm1(MECP2)Cya}
Targeted Allele Detail

Summary

• Symbol: Mecp2^{tm1(MECP2)Cya}
• Name: methyl CpG binding protein 2; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657302
• Synonyms: Mecp2^{tm1(hMECP2)Cya}
• Gene: Mecp2 Location: ChrX:73070198-73129296 bp, - strand Genetic Position: ChrX, 37.63 cM
• Alliance: Mecp2^{tm1(MECP2)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mecp2^{tm1(MECP2)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MECP2 (4204)

  Mecp2

  (MGI:99918)

• Mutation details: The mouse MECP2 protein coding sequence for amino acids 10484 was replaced with the corresponding human MECP2 protein coding sequence for amino acids 10486 because the coding sequences for amino acids 19 of mouse and human MECP2 proteins are identical. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mecp2 Mutation: 43 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)