Isr(HSA11;CD3)1Cya
Targeted Allele Detail

Summary

• Symbol: Isr(HSA11;CD3)1Cya
• Name: interspecies replacement, human Chr 11, Cyagen Biosciences 1
• MGI ID: MGI:7657287
• Synonyms: IS(9CD3)1Cya, Is(HSACD3)Cya>
• Gene: Isr(HSA11;CD3)1Cya Location: unknown Genetic Position: Chr9, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/cAn

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Isr(HSA11;CD3)1Cya expresses 3 genes
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD3D (915)

  Cd3d	(MGI:88331)

  human

  CD3E (916)

  Cd3e	(MGI:88332)

  human

  CD3G (917)

  Cd3g	(MGI:88333)

• Mutation details: The mouse Cd3e, Cd3d, and Cd3g genes which encode the three components of the CD3 complex, Cd3, Cd3, and Cd3, were replaced by the corresponding human homologous genes. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Isr(HSA11;CD3)1Cya Mutation: 0 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)