Gdf15^{em1(GDF15)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gdf15^{em1(GDF15)Cya}
• Name: growth differentiation factor 15; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657251
• Synonyms: Gdf15^{em1(hGDF15)Cya}
• Gene: Gdf15 Location: Chr8:71082043-71085106 bp, - strand Genetic Position: Chr8, 34.15 cM, cytoband C1
• Alliance: Gdf15^{em1(GDF15)Cya} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Gdf15^{em1(GDF15)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GDF15 (9518)

  Gdf15

  (MGI:1346047)

• Mutation details: The mouse Gdf15 endogenous domain (aa.31~303) was replaced with the human GDF15 domain (aa.30~308). The murine signal peptide (aa.1~30) was remained. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gdf15 Mutation: 26 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)