Alb^tm1(ALB)Cya
Targeted Allele Detail

Summary

• Symbol: Alb^tm1(ALB)Cya
• Name: albumin; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657208
• Synonyms: Alb^tm1(hALB)Cya
• Gene: Alb Location: Chr5:90608756-90624461 bp, + strand
• Alliance: Alb^tm1(ALB)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Alb^tm1(ALB)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ALB (213)

  Alb	(MGI:87991)

• Mutation details: Both the mouse Alb gene and the human ALB gene contain 15 exons. The mouse Alb gene sequence (approximately 10kb upstream of Exon 1 to approximately 500bp downstream of Exon 15) was replaced with the human ALB gene sequence (approximately 100kb upstream of Exon 1 to approximately 1kb downstream of Exon 15) using embryonic stem cell (ES) gene editing technology. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alb Mutation: 94 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)