Ace2^tm3(ACE2)Cya
Targeted Allele Detail

Summary

• Symbol: Ace2^tm3(ACE2)Cya
• Name: angiotensin converting enzyme 2; targeted mutation 3, Cyagen Biosciences
• MGI ID: MGI:7657205
• Synonyms: Ace2^{tm3(LoxP-hACE2-LoxP)}
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^tm3(ACE2)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Ace2^tm3(ACE2)Cya expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• Mutation details: The endogenous mouse Ace2 sequence was replaced with the loxP site-flanked hACE2's coding sequence (CDS) while retaining the sequence encoding the mouse ACE2 protein signal peptide. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 72 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)