Maf1^tm1Lnh
Targeted Allele Detail

Summary

• Symbol: Maf1^tm1Lnh
• Name: MAF1 homolog, negative regulator of RNA polymerase III; targeted mutation 1, Nouria Hernandez
• MGI ID: MGI:7645448
• Synonyms: floxed Maf1
• Gene: Maf1 Location: Chr15:76235494-76238578 bp, + strand Genetic Position: Chr15, 35.75 cM, cytoband E1
• Alliance: Maf1^tm1Lnh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222253
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert one loxP site in intron 2 (481 bp 5' of the start codon), an FRT-flanked neomycin resistance (neo) cassette in exon 8, followed by a loxP site (221 bp 3' of the stop codon). (J:222253)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf1 Mutation: 11 strains or lines available

References

• Original: J:222253 Bonhoure N, et al., Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev. 2015 May 1;29(9):934-47
• All: 2 reference(s)