Ino80^em1Boet
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ino80^em1Boet
• Name: INO80 complex subunit; endonuclease-mediated mutation 1, Thomas Boettger
• MGI ID: MGI:7645200
• Gene: Ino80 Location: Chr2:119203523-119308168 bp, - strand Genetic Position: Chr2, 59.97 cM, cytoband E5
• Alliance: Ino80^em1Boet page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology replaced the TAA codon with a sequence encoding for a linker and a V5-tag followed by STOP codons. (J:306156)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ino80 Mutation: 438 strains or lines available

References

• Original: J:306156 Schutt C, et al., Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy. EMBO J. 2020 Nov 16;39(22):e105098
• All: 1 reference(s)