Slc27a3^em1Lmjn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc27a3^em1Lmjn
• Name: solute carrier family 27 (fatty acid transporter), member 3; endonuclease-mediated mutation 1, Lauryl Nutter
• MGI ID: MGI:7643529
• Gene: Slc27a3 Location: Chr3:90292546-90297245 bp, - strand Genetic Position: Chr3, 39.22 cM, cytoband F2
• Alliance: Slc27a3^em1Lmjn page

Mutation origin

• Strain of Origin: C57BL/6NCrl-Slc27a3^em1(IMPC)Tcp/Tcp

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Bxb1 integrase mRNA and a DNA minicircle containing a single Bxb1 attB-GT site and loxP-flanked genomic DNA (Chr3:90294858 to 90295155 GRCm39) including exon ENSMUSE00001308785 were microinjected into C57BL/6NCrl-derived embryos with the Slc27a3^em1(IMPC)Tcp (MGI:7425980) allele that contains a single Bxb1 attB-GT site at the deletion junction. This insertion is predicted to restore wild-type gene function and create a conditional allele. Cre-mediated deletion of the loxP-flanked region is predicted to generate a null allele equivalent to Slc27a3. (J:344138)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc27a3 Mutation: 29 strains or lines available

References

• Original: J:344138 The Centre for Phenogenomics, Strains and alleles submitted by The Centre for Phenogenomics. MGI Direct Data Submission. 2024
• All: 1 reference(s)