Usp46^em1Utr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp46^em1Utr
• Name: ubiquitin specific peptidase 46; endonuclease-mediated mutation 1, University of Tsukuba Laboratory Animal Resource Center
• MGI ID: MGI:7639920
• Synonyms: Usp46 flox KI
• Gene: Usp46 Location: Chr5:74159387-74229070 bp, - strand Genetic Position: Chr5, 39.33 cM
• Alliance: Usp46^em1Utr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted into introns 3 and 4 using sgRNAs and an ssODN plasmid template with CRISPR/Cas9 technology. (J:317830)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp46 Mutation: 79 strains or lines available

References

• Original: J:317830 Kuno A, et al., DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes. PLoS Biol. 2022 Jan;20(1):e3001507
• All: 1 reference(s)