Tg(Drd2-tTA)1Kftnk
Transgene Detail

Summary

• Symbol: Tg(Drd2-tTA)1Kftnk
• Name: transgene insertion 1, Kenji Tanaka
• MGI ID: MGI:7621378
• Synonyms: Drd2-tTA
• Transgene: Tg(Drd2-tTA)1Kftnk Location: unknown
• Alliance: Tg(Drd2-tTA)1Kftnk page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Tg(Drd2-tTA)1Kftnk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drd2 (MGI:94924)

• Mutation details: A tetracycline transcriptional activator (tTA) gene and an SV40 polyadenylation signal was inserted into the translation initiation site of the dopamine receptor type 2 (Drd2) gene in mouse bacterial artificial chromosome (BAC) DNA (clone RP23-161H15). One founder line was obtained. (J:244785)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:244785 Tsutsui-Kimura I, et al., Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation. Nat Commun. 2017 Feb 01;8:14304
• All: 5 reference(s)