Lgr4^em1Kori
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lgr4^em1Kori
• Name: leucine-rich repeat-containing G protein-coupled receptor 4; endonuclease-mediated mutation 1, Vladimir Korinek
• MGI ID: MGI:7619083
• Synonyms: Lgr4^3HA
• Gene: Lgr4 Location: Chr2:109747992-109844602 bp, + strand Genetic Position: Chr2, 56.65 cM
• Alliance: Lgr4^em1Kori page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, No functional change)
• Mutation: Insertion
• Mutation details: TALEN-mediated genome editing technology was used to insert a 3HA tag immediately downstream of the sequence encoding the signal peptide of the protein. A full length 3HALGR4 fusion protein is expressed. (J:252705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lgr4 Mutation: 92 strains or lines available

References

• Original: J:252705 Kriz V, et al., Establishment of a tagged variant of Lgr4 receptor suitable for functional and expression studies in the mouse. Transgenic Res. 2017 Oct;26(5):689-701
• All: 1 reference(s)