Sh3bp1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sh3bp1^em1(IMPC)J
• Name: SH3-domain binding protein 1; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7618352
• Gene: Sh3bp1 Location: Chr15:78783994-78796247 bp, + strand Genetic Position: Chr15, 37.7 cM
• Alliance: Sh3bp1^em1(IMPC)J page
• IMPC: Sh3bp1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences: CACACGGTACTAAGGATCCG and GCTGAAAGCTCTGTAAAAGT. This resulted in a 508 bp internal deletion of Chr15:78,904,108-78,904,615 (GRCm38/mm10) that removes exons ENSMUSE00001261102 and ENSMUSE00001241677. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sh3bp1 Mutation: 37 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)