Israa^tm1.1Famd
Targeted Allele Detail

Summary

• Symbol: Israa^tm1.1Famd
• Name: immune system associated SCR family kinase partner; targeted mutation 1.1, M Dahmani Fathallah
• MGI ID: MGI:7612213
• Gene: Israa Location: Chr14:25603937-25606060 bp, + strand Genetic Position: Chr14, Syntenic
• Alliance: Israa^tm1.1Famd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288760
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site and FRT-flanked neo cassette were inserted upstream of exon 1, an IRES-eGFP was inserted in exon 1 downstream of the coding sequence, and a second loxP site was inserted downstream of exon 2 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:288760)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Israa Mutation: 0 strains or lines available

References

• Original: J:288760 Ben Khalaf N, et al., The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling. Mol Immunol. 2019 Jul;111:209-219
• All: 1 reference(s)