Nron^tm1.1Yaos
Targeted Allele Detail

Summary

• Symbol: Nron^tm1.1Yaos
• Name: non-protein coding RNA, repressor of NFAT; targeted mutation 1.1, Yao Sun
• MGI ID: MGI:7611964
• Synonyms: Nron^flox
• Gene: Nron Location: Chr2:33695828-33703603 bp, + strand Genetic Position: Chr2, 22.53 cM
• Alliance: Nron^tm1.1Yaos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345831
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked pGK-neomycin cassette and second loxP site were inserted downstream of exon 3. The neomycin cassette was removed via flp-mediated recombination leaving exons 2-3 flanked by loxP sites. (J:345831)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nron Mutation: 1 strain or line available

References

• Original: J:345831 Zhang R, et al., LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption. Int J Oral Sci. 2020 May 9;12(1):14
• All: 3 reference(s)